Daniel Jones had a breakout game in his Giants debut, but can he deliver a repeat performance in his first NFC East rivalry game. In Buffalo, Tom Brady will try to continue his dominance against the Bills, while the Chiefs and Lions will go head-to-head in a battle of undefeated teams.
Check out: Week 4 picks against the spread
All odds via BetMGM.
1:00 p.m. ET: Titans (1-2) at Falcons (1-2) - CBS
Point spread: Falcons -4.5
1:00 p.m. ET: Redskins (0-3) at Giants (1-2) - FOX
Point spread: Giants -2.5
1:00 p.m. ET: Chargers (1-2) at Dolphins (0-3) - CBS
Point spread: Chargers -16.5
1:00 p.m. ET: Raiders (1-2) at Colts (2-1) - CBS
Point spread: Colts -6.5
1:00 p.m. ET: Panthers (1-2) at Texans (2-1) - FOX
Point spread: Texans -4.5
1:00 p.m. ET: Chiefs (3-0) at Lions (2-0-1) - FOX
Point spread: Chiefs -6.5
1:00 p.m. ET: Browns (1-2) at Ravens (2-1) - CBS
Point spread: Ravens -6.5
1:00 p.m. ET: Patriots (3-0) at Bills (3-0) - CBS
Point spread: Patriots -7.5
4:05 p.m. ET: Buccaneers (1-2) at Rams (3-0) - FOX
Point spread: Rams -10.5
4:05 p.m. ET: Seahawks (2-1) at Cardinals (0-2-1) - FOX
Point spread: Seahawks -4.5
4:25 p.m. ET: Vikings (2-1) at Bears (2-1) - CBS
Point spread: Bears -2.5
4:25 p.m. ET: Jaguars (1-2) at Broncos (0-3) - CBS
Point spread: Broncos -3.5
8:20 p.m. ET: Cowboys (3-0) at Saints (2-1) - NBC
Point spread: Cowboys -2.5
Monday Night Football
8:15 p.m. ET: Bengals (0-3) at Steelers (0-3) - ESPN
Point spread: Steelers -4.5