The Philadelphia Eagles have the best record in the NFC this season at 10-1, but they will likely be underdogs for the first time all season when they take on the 8-3 San Francisco 49ers in a rematch of last season’s NFC championship game.

The Eagles are currently 2.5-point home underdogs against the 49ers at most sportsbooks, with a few books even showing Eagles +3. Given the way the line is trending, barring significant injuries on the 49ers side, San Francisco will go off as the favorite.

That means that Philadelphia will likely become the first team in at least 20 years that a 10-1 or better team is a home underdog when its starting quarterback is playing, according to Bet Labs.

The other two instances were in Week 17 in 2020 when the 14-1 Kansas City Chiefs were 7-point underdogs against the Los Angeles Chargers and in Week 17 in 2011 when the 14-1 Green Bay Packers started Matt Flynn versus the Detroit Lions and were 6.5-point underdogs.

Some sportsbooks opened with the Eagles as a short favorite before respected bettors pushed the 49ers to favoritism. Even some bookmakers were surprised that the line has hit San Francisco -3 in some places. Philadelphia was a 3-point favorite at Caesars Sportsbook when it opened lines back in the summer for all 17 games.

“I think it’s a product of the 49ers now being healthy and playing so well, and the Eagles being outplayed but still finding a way to win,” Chuck Esposito, sportsbook director at Station Casinos told For The Win via text. “Also, it’s a huge revenge game for the 49ers. I thought if the 49ers were the favorite, though, it would be no more than 1.”

It should be a terrific matchup on Sunday, and one that bettors and fans alike will eagerly anticipate watching.